Anti-Clostridium difficile toxin B Antibody

Offered through the Antibodies.com primary antibodies catalogue, this Protein A purified mouse monoclonal reagent is raised against Clostridium difficile Toxin B (TcdB), the large glucosyltransferase cytotoxin that inactivates Rho-family GTPases and is a key virulence determinant of C. difficile. The antibody is supplied as a 1 mg pack of purified monoclonal antibody in liquid form, conjugated to nothing (Unconjugated), and is of the IgG1 isotype from a Mouse host. It is validated for ELISA and IFA workflows, including immunofluorescence staining of infected cultures or tissue sections, and the listing is intended for research use only. According to the supplier specification the reagent is specific for C. difficile Toxin B with no significant cross-reactivity toward Toxin A, an important consideration when working with stool or culture samples that may contain both toxins. For short-term handling the antibody should be stored at 2 to 8 °C and is generally stable under those conditions for routine use; for longer-term keeping, aliquots are typically frozen at −20 °C, with repeated freeze-thaw cycles avoided to preserve activity. The unconjugated format leaves the reagent flexible for downstream labelling, while the Protein A purified IgG1 backbone provides a clean background in immunoassays. This Antibodies.com product complements matched-pair ELISA and lateral-flow assay development as either capture or detection antibody for C. difficile toxin B detection.