Anti-CLIC4 Antibody

CLIC4 (Chloride Intracellular Channel Protein 4) is a ~29 kDa member of the chloride intracellular channel family that localizes to the cytoplasm, nucleus, and mitochondrial membranes, where it contributes to chloride conductance, cytoskeletal remodeling, and apoptotic signaling. This Rabbit polyclonal antibody from Antibodies.com is raised against CLIC4 and supplied as an unconjugated, 100 µl aliquot suitable for western blot and immunohistochemistry workflows. The antibody cross-reacts with human and mouse samples, enabling studies of CLIC4 expression across rodent models and patient-derived material.

The polyclonal format provides recognition of multiple epitopes on the target protein, which is helpful when analyzing post-translational modifications or isoform-specific expression patterns. The unconjugated presentation allows the researcher to pair the reagent with a chosen secondary label and detection chemistry, supporting chromogenic IHC, immunofluorescence, or chemiluminescent western blot. Aliquoting upon arrival and storage at -20 °C preserves activity across repeated freeze-thaw cycles for ongoing investigation of CLIC4 in keratinocyte differentiation, neuronal chloride homeostasis, and tumor-suppressor pathways.