Anti-CLIC4 Antibody

Raised in rabbit, this unconjugated polyclonal antibody recognizes chloride intracellular channel protein 4 (CLIC4), a multifunctional ion channel that localizes to the cytoplasm, nucleus, and mitochondria of mammalian cells. CLIC4 participates in TNF-α–driven apoptosis, p53-mediated cell death, reactive oxygen species regulation, and cytoskeletal remodeling, and it has been studied in the context of tumor suppression, epithelial differentiation, pulmonary vascular remodeling, and bone metabolism research. The reagent is validated for Western blot (WB) and immunohistochemistry (IHC) on human and mouse samples, supporting investigation of CLIC4 expression across normal and diseased tissues. Supplied by Antibodies.com as 100 µl of polyclonal antiserum, the unconjugated format allows flexible pairing with the secondary labels of the researcher's choice for diverse detection workflows, and storage at standard refrigerator temperatures preserves activity for routine laboratory use.