Anti-Cleaved-KLK11 (I54) Antibody

This rabbit polyclonal antibody from Antibodies.com is raised against the cleaved form of Kallikrein-11 (KLK11) at the I54 cleavage site, supporting research into serine protease activation, tumor progression, and hormone-responsive tissue biology. KLK11 is a secreted trypsin-like serine protease of the kallikrein family, and detection of its proteolytically processed I54 fragment is relevant to studies of prostate, brain, and other KLK11-expressing tissues.

Validated for Western Blot, the reagent recognizes KLK11 in human, mouse, and rat samples, enabling cross-species expression analysis in cell lysates and tissue homogenates. The unconjugated polyclonal is supplied as 100 µl of a 1 mg/ml stock in PBS with 0.1% Sodium Azide and 50% glycerol, packaged in a vial and ready for HRP- or fluorophore-conjugated secondary detection workflows. For storage, aliquot upon receipt to limit freeze-thaw cycles and store at -20°C; the glycerol cushion preserves activity during brief bench-top handling.

Produced in rabbit host, this primary antibody is useful to investigators characterizing KLK11 cleavage events in normal versus malignant tissue contexts where the I54-processed species serves as a meaningful biomarker of proteolytic maturation.