Anti-Cleaved-Collagen 3A1 (G1221) Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets the cleaved neoepitope of collagen type III at the G1221 cleavage site, enabling researchers to specifically detect fragmented or processed collagen III rather than intact fibrils. The reagent is unconjugated and supplied at 1 mg/ml in a buffer containing PBS with 0.1% sodium azide and 50% glycerol, a stabilizing formulation appropriate for standard laboratory handling.

Validated for western blot applications, the antibody reacts with human, mouse, and rat samples, making it broadly applicable across commonly used model organisms. The polyclonal format increases the likelihood of recognizing the target even when nearby residues vary, which is useful when probing cleaved fragments generated by endogenous proteases such as MMPs. Each vial contains 100 µl of antibody, sufficient for multiple blotting experiments when used at typical working dilutions.

Recommended storage is at -20 °C in aliquots to preserve activity and minimize freeze-thaw cycles, and the product is intended for research use only. Scientists studying fibrosis, connective tissue turnover, wound healing, or extracellular matrix remodeling will find this antibody a focused tool for monitoring type III collagen proteolysis.