Anti-Cleaved-Caspase-8 (D384) Antibody

Manufactured by Antibodies.com, this affinity-purified rabbit polyclonal reagent is raised against a synthesized peptide derived from the C-terminal region of human Caspase-8 and is designed to detect the activated, cleaved fragment of Caspase-8 generated adjacent to aspartate 384. Supplied as a 50 µl liquid at a concentration of 1 mg/ml in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, the unconjugated antibody is validated for Western blot and ELISA applications and reacts specifically with human samples. Endogenous levels of the activated Caspase-8 fragment can be visualized in lysates such as 293 cells by Western blot, making this reagent well suited to apoptosis research and studies of extrinsic death-receptor signalling pathways. The polyclonal host (Rabbit) ensures broad epitope coverage for reliable recognition of the D384 cleavage site, and the product should be stored at –20 °C where it remains stable for up to one year. Intended for research use only, it is not validated for diagnostic or therapeutic applications and is dispatched from Cambridge, UK, with a typical lead time of 4–6 business days.