Anti-Cleaved-Caspase-4 p20 (Q81) Antibody

Rabbit polyclonal antibodies raised against the cleaved p20 subunit of human caspase-4 support dissection of non-canonical inflammasome activation and pyroptotic cell death pathways. This unconjugated reagent from Antibodies.com recognizes an epitope at glutamine 81, the autoprocessing cleavage site, allowing selective detection of the catalytically active fragment rather than the full-length zymogen. Validated for Western blot, immunohistochemistry, and ELISA on human samples, the antibody is supplied as 100 µl of polyclonal serum raised in a rabbit host. It is intended for research use only in laboratory studies of innate immune signaling, intracellular LPS sensing, and inflammatory disease models where gasdermin D-mediated pyroptosis is of interest, including work in monocytes, macrophages, and epithelial tissues.