Anti-Cleaved-Caspase-1 (D210) Antibody

Manufactured by Antibodies.com, this affinity-purified rabbit polyclonal reagent is raised against a synthesized peptide mapping to the internal region of human Caspase-1 and selectively detects the activated fragment of Caspase-1 generated by cleavage adjacent to aspartate 210 (D210). The antibody is supplied as a 50 µl liquid formulation in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, at a working concentration of 1 mg/ml, and is unconjugated for straightforward incorporation into standard detection workflows. Validated applications include Western blotting, immunohistochemistry and ELISA on human samples, making it well suited to studies of inflammasome activation, pyroptosis and IL-1β maturation pathways. The host species is rabbit, the clonality is polyclonal, the immunoglobulin class is IgG, and the reagent is recommended to be stored at –20 °C for up to one year from the date of receipt, with repeat freeze–thaw cycles avoided. Provided through AFMS for research use only, the product is dispatched from Cambridge (UK) with a typical lead time of 4–6 business days, giving laboratories a reliable and well-characterized tool for probing cleaved Caspase-1 in cell and tissue lysates.