Anti-CLDND2 Antibody

CLDND2 (Claudin Domain Containing 2) is a multi-pass transmembrane protein implicated in tight junction biology and cell-cell adhesion. This unconjugated rabbit polyclonal antibody recognizes endogenous CLDND2 in both human and mouse samples, supporting cross-species comparative studies of claudin-domain-containing membrane proteins.

The reagent is supplied as 100 µl of polyclonal antiserum raised in rabbit and is validated for Western blot and immunohistochemistry workflows. Researchers can apply it to characterize membrane-associated claudin-domain proteins in cell lysates and fixed tissue sections, including investigations into epithelial barrier function and protein trafficking at the plasma membrane.

For best results, store the antibody refrigerated, aliquot upon first use, and limit freeze-thaw cycles to preserve antibody activity. A species-matched HRP- or fluorophore-conjugated secondary is recommended for signal detection. For research use only, this Antibodies.com primary antibody offers reliable reactivity across two commonly studied mammalian species and serves as a tool for laboratories mapping tight junction composition.