Anti-CLDN8 Antibody

Raised in rabbit against the tight-junction transmembrane protein Claudin-8, this unconjugated polyclonal IgG primary antibody is supplied by Antibodies.com in a 100 µl volume and validated for Western blot (WB) detection in mouse and rat samples. Claudin-8 contributes to epithelial tight-junction strand formation in the distal nephron and intestinal epithelium, where it shapes paracellular ion selectivity and barrier integrity, making antibodies against it useful for kidney tubular transport, gut permeability, and epithelial polarity studies.

Because the reagent is provided unconjugated, it pairs flexibly with a laboratory's preferred secondary system, whether HRP, fluorescent, or biotinylated, depending on the Western blot workflow. The IgG fraction is delivered as a ready-to-use liquid aliquot. For best antibody stability, store refrigerated and limit freeze-thaw cycles to preserve antigen-binding activity over the product's shelf life.