Anti-CLDN6 Antibody

This rabbit polyclonal reagent from Antibodies.com specifically recognizes human Claudin-6 (CLDN6), a four-transmembrane tight junction protein that is largely silent in adult tissues but re-emerges in several solid tumor types. Researchers in oncology and developmental biology rely on this unconjugated antibody to investigate tight junction organization, epithelial barrier function, and CLDN6 as a candidate cancer immunotherapy target.

Validated across western blot, immunohistochemistry, and immunofluorescence workflows, the antibody supports detection of endogenous CLDN6 in cell lysates, formalin-fixed paraffin-embedded tissues, and adherent cell lines. The polyclonal format provides broader epitope coverage than monoclonal alternatives, which is helpful when probing low-abundance targets or when the antigen is partially masked by fixation chemistry.

Each vial contains 100 µL of unconjugated reagent, allowing individual labeling or signal-amplification strategies to be tailored per application. Host species is rabbit, reactivity is confirmed for human samples, and the product is supplied as a liquid stock suitable for direct dilution into standard blocking and incubation buffers.