Anti-CLDN2 Antibody

Raised in rabbit and affinity-purified against a recombinant human CLDN2 immunogen, this polyclonal reagent from Antibodies.com is supplied at 1.0 mg/mL in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol. The unconjugated antibody is offered in a 50 µL format and is validated for Western blotting (WB) and immunocytochemistry/immunofluorescence (ICC/IF), with demonstrated staining of endogenous CLDN2 in human HeLa cells. It specifically detects total endogenous Claudin-2 (also known by the synonym SP82), a tight-junction transmembrane protein, and is reactive with human samples. The host species is rabbit, the clonality is polyclonal, and the conjugate is unconjugated, allowing flexible downstream labelling with secondary reagents of the user's choice. Shipping is performed at 4 °C; upon receipt, the antibody should be aliquoted and stored at –20 °C, with repeated freeze/thaw cycles avoided to preserve activity. For research use only and not intended for diagnostic or therapeutic applications, this reagent provides a reliable tool for laboratories studying tight-junction biology, epithelial barrier function and CLDN2-associated signalling in human cell models.