Anti-CLDN19 Antibody

Raised in rabbit as an unconjugated polyclonal IgG preparation, this Antibodies.com reagent targets the tight junction protein CLDN19 (claudin-19) for detection in human, mouse, and rat samples by Western blot. Each vial contains 100 µl of antibody, supplied as a ready-to-use liquid for immunoblotting of tissue lysates and cultured cell extracts.

Claudin-19 is a structural component of tight junction strands in epithelial sheets, with prominent expression in renal tubules and the retinal pigment epithelium, where it shapes paracellular ion flux and barrier selectivity. Variants in the CLDN19 gene are linked to familial hypomagnesemia with hypercalciuria and nephrocalcinosis, conditions frequently complicated by ocular involvement, so well-validated antibodies against this claudin support research into epithelial transport, kidney physiology, retinal biology, and related disease mechanisms.

For everyday handling, aliquot on arrival and store refrigerated; protect from light and minimise freeze-thaw cycles to preserve activity. Intended for research use only.