Anti-CLDN14 Antibody

CLDN14 (Claudin-14) belongs to the claudin family of tetraspan transmembrane proteins that form the structural backbone of tight junctions in epithelial and endothelial cell sheets. This rabbit polyclonal IgG antibody, raised against the human target, recognizes CLDN14 on Western blots and is validated for use with human and mouse samples. Researchers investigating DFNB29 hereditary hearing loss, tight junction biology, paracellular ion permeability in the renal thick ascending limb of Henle, or auditory hair cell development routinely rely on this Antibodies.com reagent to detect endogenous protein in tissue lysates and cell culture models. Each vial is supplied as 100 µl of unconjugated, affinity-purified antiserum suitable for immunoblotting experiments; aliquot upon first use and store at -20°C to preserve activity across multiple freeze-thaw cycles. The unconjugated format accommodates downstream chemiluminescent or colorimetric detection chemistries without species cross-reactivity interference, supporting reproducibility across independent Western blot runs.