Anti-CLDN14 Antibody

Raised against CLDN14 (Claudin-14), a four-transmembrane tight junction protein whose loss-of-function mutations underlie autosomal recessive nonsyndromic hearing loss (DFNB29) and modulate paracellular calcium reabsorption in the thick ascending limb of the renal tubule. The reagent from Antibodies.com is an unconjugated rabbit IgG polyclonal with reactivity validated against human CLDN14, supplied as a 200 µL vial at working concentration ready for Western blot (WB) detection in cell lysates and tissue homogenates. For optimal stability, aliquot upon arrival, store at -20°C, and limit freeze-thaw cycles; brief room temperature handling is acceptable during use. Pairs cleanly with HRP-conjugated anti-rabbit secondary for chemiluminescent readout and is well suited to membrane-enriched fractions used in epithelial barrier and inner-ear research.