Anti-CLDN14 Antibody

CLDN14 (Claudin-14) is a four-transmembrane-domain tight junction protein that regulates paracellular ion permeability in epithelial barriers and is most studied for its role in autosomal recessive nonsyndromic hearing loss (DFNB29) and renal magnesium handling. This rabbit polyclonal IgG antibody from Antibodies.com is raised against human CLDN14 and is validated for Western blot detection of the target in cell and tissue lysates. Supplied as 100 µl of unconjugated antiserum, the polyclonal format offers multi-epitope recognition for consistent signal across immunoblotting workflows. Recommended handling includes short-term refrigerated storage and aliquoting to limit freeze-thaw cycles, preserving antibody activity for ongoing research programs. The host species is rabbit, the clonality is polyclonal, and reactivity is restricted to human samples, making it applicable to studies investigating claudin biology, hearing loss genetics, and kidney ion transport. For research use only.