Anti-CLCC1 Antibody

The polyclonal rabbit antibody against CLCC1 offered by Antibodies.com recognizes the chloride channel CLIC-like 1 protein, an endoplasmic reticulum-resident integral membrane protein also referred to as MCLC. CLCC1 has drawn attention in vision research because loss-of-function variants in the gene have been linked to autosomal recessive retinitis pigmentosa, and the protein has been characterized as a candidate anion channel contributing to ionic homeostasis in the ER lumen. This unconjugated reagent is supplied as 100 µl of polyclonal antiserum raised in rabbit and validated for western blot, immunohistochemistry, and immunofluorescence workflows on human samples. Investigators studying ER stress responses, photoreceptor degeneration, and chloride conductance mechanisms use this reagent to probe endogenous CLCC1 expression in cultured cells and tissue sections.