Anti-Claudin 7 Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent is raised against Claudin 7 (CLDN7), a tight-junction transmembrane protein widely studied in epithelial barrier biology, cancer invasion, and gastrointestinal mucosal research. The antibody was generated using a synthesized peptide derived from the human Claudin 7 sequence and was affinity-purified from rabbit antiserum by affinity-chromatography against the epitope-specific immunogen, yielding a preparation that detects endogenous levels of total Claudin 7. It is supplied as50 µl of unconjugated polyclonal antibody at 1.0 mg/mL, formulated in phosphate-buffered saline (without Mg²⁺ and Ca²⁺), pH 7.4, with 150 mM NaCl, 0.02% sodium azide, and 50% glycerol as a cryoprotectant; the host species is Rabbit and the immunoglobulin class is IgG. Validated applications include Western Blot (WB) and Immunohistochemistry (IHC), and the reagent has been confirmed to react with Human, Mouse, and Rat samples, making it suitable for cross-species studies of tight-junction integrity in cell lines, tissue sections, and primary cultures. The product is shipped at 4°C; upon receipt it should be aliquoted and stored at –20°C, with freeze/thaw cycles avoided to preserve binding activity. Intended for research use only, this Antibodies.com primary antibody offers a reliable tool for laboratories characterizing Claudin 7 expression in normal epithelia, tumour microenvironments, and barrier-function models.