Anti-Claudin 5 Antibody

Manufactured by Antibodies.com, this primary antibody is a rabbit polyclonal reagent raised against Claudin 5 (CLDN5), a tight-junction transmembrane protein widely used as a marker in vascular and endothelial biology studies. The antibody was generated using a synthesized peptide derived from human CLDN5 as immunogen and was affinity-purified from rabbit antiserum by affinity-chromatography on an epitope-specific column, ensuring selective recognition of endogenous levels of total CLDN5 protein. It is supplied as an unconjugated IgG at a concentration of 1.0 mg/mL in a 50 µl volume, formulated in phosphate-buffered saline without Mg²⁺ and Ca²⁺ (pH 7.4) with 150 mM NaCl, 0.02% sodium azide and 50% glycerol to preserve activity during routine handling. The reagent is validated for Western blotting (WB) and immunohistochemistry (IHC) on human samples, making it suitable for both cell-based and tissue-based detection workflows in cardiovascular, neuroscience and cancer research. The host species is rabbit and the clonality is polyclonal, providing a broad epitope coverage against the target protein. For shipping, the vial is dispatched at 4 °C and, upon receipt, should be aliquoted and stored at −20 °C, with repeated freeze/thaw cycles avoided to maintain antibody integrity. This product is intended for research use only and is not validated for diagnostic or therapeutic applications.