Anti-Claudin-5 Antibody

This polyclonal reagent from Antibodies.com targets Claudin-5, a ~23 kDa tight-junction transmembrane protein that seals endothelial cell contacts and is heavily studied in vascular biology and neuroscience research. Raised in Rabbit and supplied as an unconjugated preparation in a 100 µl vial, the antibody is validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows across Human, Mouse, and Rat samples.

Researchers commonly apply it to map paracellular barrier integrity in cerebral microvessels, characterize leaky vessels in glioblastoma and stroke models, and profile Claudin-5 downregulation in neuroinflammatory disease tissue. The polyclonal format allows recognition of multiple epitopes on the target, which is helpful when probing primary endothelial cultures or archival paraffin sections where epitope masking can occur.

Aliquot upon arrival to limit freeze-thaw cycles, store refrigerated, and protect from light for long-term stability. For research use only.