Anti-Claudin-4 Antibody

Raised in rabbit, this polyclonal reagent from Antibodies.com binds the tight-junction transmembrane protein claudin-4 and cross-reacts with human, mouse, and rat samples. Claudin-4 is roughly 27 kDa and is widely used as a marker of epithelial barrier integrity in gastrointestinal, pancreatic, and ovarian tissue research, where loss or mislocalization of the protein signals disrupted tight junctions and altered tissue architecture. The unconjugated antibody is supplied as 100 µl of liquid and is validated for western blot, immunohistochemistry, immunofluorescence, and ELISA workflows in research laboratories. Typical uses include probing claudin-4 abundance in epithelial cell monolayers, characterizing tight-junction remodeling in mucosal disease models, and evaluating tumor-versus-non-tumor margins in oncology studies.