Anti-Claudin-3 Antibody

Claudin-3 is a ~23 kDa transmembrane tight junction protein encoded by the CLDN3 gene, critical for epithelial barrier integrity and paracellular permeability. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the target and validated across western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, making it versatile for both expression profiling and localization studies in epithelial and cancer research contexts.

Cross-reactivity has been confirmed in human, mouse, and rat samples, supporting translational work across model organisms and patient-derived specimens. Supplied as 100 µl of ready-to-use stock, the antibody is suited to probing tight junction organization in tissues where Claudin-3 mislocalization has been linked to tumor progression and epithelial-mesenchymal transition, including studies of breast, ovarian, and gastrointestinal malignancies.