Anti-Claudin-1 Antibody

Raised in rabbit against the tight junction membrane protein Claudin-1, this polyclonal antibody from Antibodies.com is supplied as 100 µl of unconjugated serum for Western blot and immunohistochemistry workflows. The reagent recognizes human, mouse, and rat Claudin-1, supporting studies of epithelial barrier integrity, hepatocyte polarity, and hepatitis C virus entry, where Claudin-1 functions as a co-receptor for viral attachment at the basolateral surface of hepatocytes. As a roughly 22 kDa tetraspan transmembrane protein, Claudin-1 is frequently investigated in cancer invasion and metastasis models, inflammatory bowel disease research, and dermatology studies of stratum corneum permeability. The unconjugated format allows flexible pairing with custom reporter conjugates, secondary detection systems, or fluorophore labeling tailored to a given experimental design. Each lot is intended for research use only and is validated for the listed species reactivities and application types.