Anti-CKS1 Antibody

This polyclonal reagent from Antibodies.com targets CKS1 (CDC28 protein kinase regulatory subunit 1B), a cell-cycle regulatory protein that cooperates with the SCF^Skp2 ubiquitin ligase complex to promote p27^Kip1 degradation during the G1/S transition. Raised in rabbit, the unconjugated antibody is supplied as 100 µl of ready-to-use reagent and is validated for western blot and immunofluorescence workflows on human and mouse samples.

The reagent recognizes endogenous CKS1 in whole-cell lysates and fixed cells, supporting studies of cyclin-dependent kinase signaling, proliferation markers, and tumor suppressor turnover. Cancer researchers investigating breast, lung, and colorectal tumor models frequently pair CKS1 detection with p27 and Skp2 staining to profile cell-cycle deregulation. The polyclonal format offers multiple epitope recognition, which can be useful where post-translational modification or splice variation matters.

Store refrigerated and protect from light; aliquot upon receipt if extended storage is planned. For research use only; not intended for diagnostic or therapeutic applications.