Anti-CHUK (phospho T23) Antibody

The phospho-T23 site on CHUK (also known as IKKα) marks an activating modification within the canonical NF-κB signaling cascade, and this rabbit polyclonal reagent from Antibodies.com is raised specifically against that phosphorylated epitope. Supplied as a 100 µL aliquot of unconjugated IgG, it is validated for Western blot and immunohistochemistry workflows and recognizes the human, mouse, and rat kinase, supporting cross-species studies of IKK complex regulation. Researchers in inflammation, innate immunity, and oncology apply CHUK phospho-T23 detection to monitor pathway activation status in cell lysates and fixed tissue sections, since T23 phosphorylation reflects upstream kinase activity and correlates with IKK complex assembly. The polyclonal format provides broader epitope coverage than a monoclonal, which is useful when phospho-signals are weak or when probing denatured samples, and the unconjugated format leaves detection chemistry open so laboratories can pair the antibody with HRP-, biotin-, or fluorophore-conjugated secondaries. Store at -20 °C in working aliquots to preserve phospho-epitope integrity, and minimize freeze-thaw cycles to retain activity. This primary antibody is intended for research use only.