Anti-Chromogranin A Antibody [S27-1]

The S27-1 monoclonal antibody recognizes Chromogranin A (CHGA), a roughly 49 kDa acidic glycoprotein stored in the secretory granules of neuroendocrine cells. Antibodies.com supplies this reagent at 100 ug per vial as a liquid formulation validated for western blot detection of endogenous CHGA in human, mouse, and rat samples. Researchers commonly employ the clone to investigate neuroendocrine tumor markers, pancreatic islet biology, adrenal medulla chromaffin cells, and small cell lung carcinoma models. Store the antibody aliquoted at -20 degrees C, avoiding repeated freeze-thaw cycles to preserve IgG2a binding activity. The unconjugated format allows pairing with HRP- or fluorophore-labeled secondary reagents for chemiluminescent or fluorescent western blot imaging of the chromogranin A band near 49 kDa.