Anti-CHRNB1 Antibody

The CHRNB1 gene encodes the beta-1 subunit of the nicotinic acetylcholine receptor (nAChR), a ligand-gated ion channel critical for fast synaptic transmission at neuromuscular junctions and across neuronal populations. Mutations in CHRNB1 are linked to congenital myasthenic syndromes, and the subunit has also been studied in autonomic ganglia and immune cell contexts relevant to inflammation research.

This unconjugated rabbit IgG polyclonal reagent from Antibodies.com is raised against CHRNB1 and validated for Western blot detection of the human and mouse protein. Supplied as 50 µl of ready-to-use reagent, the antibody binds the beta-1 subunit in lysates prepared from cell lines and tissue samples, supporting studies of receptor assembly, trafficking, and surface expression in neuroscience and immunology laboratories.