Anti-CHRNA1 Antibody

This rabbit polyclonal reagent targets CHRNA1, the alpha-1 subunit of the muscle-type nicotinic acetylcholine receptor that clusters at the postsynaptic membrane of the neuromuscular junction. Researchers studying congenital myasthenic syndromes, motor endplate biology, and synaptic signaling use unconjugated anti-CHRNA1 preparations for Western blot and immunohistochemistry workflows on human and mouse tissue samples. Supplied as 100 µl of polyclonal antiserum raised in rabbit, the antibody is validated for both WB and IHC applications and recognizes the target across these two species. The unconjugated format allows flexible pairing with HRP, fluorophore, or biotin secondary detection chemistries depending on experimental design. Each vial from Antibodies.com supports multiple immunoblots and staining runs when titrated appropriately, and the polyclonal nature of the reagent broadens epitope coverage for detecting endogenous CHRNA1 expression in skeletal muscle lysates, differentiated myotube cultures, and neuromuscular junction preparations.