Anti-CHRM2 Antibody

Produced in rabbit hosts and supplied as an unconjugated polyclonal reagent, this antibody targets the muscarinic acetylcholine receptor M2 (CHRM2), a G protein-coupled receptor best known for its role in parasympathetic cardiac signaling and cholinergic neurotransmission. Distributed by Antibodies.com within the Primary Antibodies category, the reagent has been validated for western blot, immunohistochemistry, and immunofluorescence workflows and reacts with human, mouse, and rat samples, supporting cross-species studies in cardiovascular and neuroscience laboratories.

The product is shipped in a 100 µl vial ready for direct incorporation into standard detection protocols, where a labeled secondary antibody provides the readout. Because the reagent is unconjugated, investigators can pair it with HRP, fluorescent, or biotinylated secondaries as their assay demands. Researchers examining heart rate regulation, smooth muscle contractility, atrial fibrillation, Alzheimer's-related pathways, or substance dependence use CHRM2 detection to map receptor distribution and expression across tissues.

The polyclonal format offers recognition of multiple epitopes on the receptor, which contributes to more robust signal across the validated applications and tolerates minor sample-to-sample variation. Storage at -20 °C in single-use aliquots is generally appropriate for polyclonal IgG preparations of this type, and the 100 µl pack size provides flexibility for both small pilot experiments and larger screening studies.