Anti-Cholera toxin Antibody

Generated in rabbit and supplied by Antibodies.com as a purified polyclonal IgG fraction, this unconjugated primary antibody targets cholera toxin, the AB5 exotoxin secreted by Vibrio cholerae that is responsible for the secretory diarrhea of clinical cholera. The reagent is provided in a 500 µL vial and has been validated for ELISA, immunofluorescence assay (IFA), and immunohistochemistry (IHC), supporting laboratories working on enteric pathogen biology, mucosal immunology, oral cholera vaccine development, and toxin neutralization studies. Because the antibody is unconjugated, it can be paired with the researcher's preferred secondary reagent for fluorescence, chromogenic, or HRP-based detection in tissue sections, infected cell culture models, and stool or environmental surveillance samples. The polyclonal format offers broader epitope coverage than a monoclonal reagent, which is useful when probing conformational epitopes on either the catalytic A subunit (CTA1/CTA2) or the pentameric B subunit (CTB) that mediates GM1 ganglioside binding. Applications include antigen distribution mapping in gut biopsy sections, confirmation of toxin expression in cell-based assays, and detection of toxin in spiked or clinical specimens. The product is intended for research use only; refrigerate on receipt and aliquot to limit freeze-thaw cycles.