Anti-CHN1 Antibody

This rabbit polyclonal antibody from Antibodies.com is raised against CHN1 (Chimerin 1), a Rac-GTPase activating protein expressed in neuronal tissues and implicated in axon guidance and cell migration signaling pathways. The unconjugated IgG reagent is validated for Western blot (WB) detection of the human target and is supplied as 100 µl of polyclonal sera. CHN1, also known as α1-chimerin or N-chimerin, contains a diacylglycerol-binding C1 domain together with a GAP-related domain that catalyzes GTP hydrolysis on Rac1, making it a useful marker for studies of neuronal development, retinal motor axon pathfinding, and germline mutations linked to Duane retraction syndrome. Because the host is Rabbit and the reagent is Polyclonal, multiple epitopes across the CHN1 sequence are recognized, supporting reproducible band detection in denatured lysate preparations used in standard WB workflows.