Anti-CHMP2B Antibody

Manufactured by Antibodies.com, this affinity-purified polyclonal reagent is raised in rabbit against the human CHMP2B protein and is supplied at a concentration of 1.0 mg/mL in a 50 µL volume. The unconjugated IgG preparation is validated for Western blotting (WB), immunohistochemistry (IHC), and immunocytochemistry/immunofluorescence (ICC/IF), with reactivity confirmed against endogenous CHMP2B in human and mouse samples. The antibody was generated using a recombinant human CHMP2B immunogen and purified by antigen-affinity chromatography to yield a reagent that specifically detects total endogenous CHMP2B protein. The formulation is buffered in phosphate-buffered saline (pH 7.4) containing 150 mM sodium chloride, 0.02% sodium azide as preservative, and 50% glycerol; the product is shipped on wet ice at 4 °C and, upon receipt, should be aliquoted and stored at −20 °C, with repeated freeze/thaw cycles avoided to preserve activity. Intended strictly for research use, this reagent is well suited to laboratories investigating ESCRT-III complex component biology, endosomal sorting pathways, and neurodegenerative disease models in which CHMP2B has been implicated, including frontotemporal dementia and amyotrophic lateral sclerosis research. Antibodies.com manufactures the antibody under catalog designation A34994, supporting reproducible performance across immunoblotting, fixed-tissue staining, and cell-based fluorescence imaging workflows.