Anti-CHMP1A Antibody

Charged Multivesicular Body Protein 1A (CHMP1A) is a core component of the ESCRT-III membrane scission machinery, and this unconjugated rabbit polyclonal antibody from Antibodies.com is raised against it for use in human and mouse research samples. CHMP1A participates in late steps of the ESCRT pathway, contributing to multivesicular body biogenesis, intraluminal vesicle formation, and the final abscission stage of cytokinesis. The antibody is validated for Western blot (WB) and immunohistochemistry (IHC) workflows.

Supplied as a 100 µl liquid aliquot in a vial, the reagent is suited to whole-cell and tissue lysate analysis on standard SDS-PAGE/WB systems, and to formalin-fixed paraffin-embedded sections in IHC, typically with citrate- or EDTA-based antigen retrieval. CHMP1A has been studied in the context of vesicular trafficking, endolysosomal dysfunction linked to neurodegenerative disease, and cell division research, making this antibody a useful tool for laboratories working on ESCRT biology and related pathways. The unconjugated format lets researchers pair it with HRP, biotin, or fluorophore-conjugated secondary antibodies of their own choice, and the polyclonal host (rabbit) provides broad epitope coverage for detecting endogenous CHMP1A.

For handling, store the vial at -20 °C in working aliquots to limit freeze-thaw cycles, briefly centrifuge before opening, and equilibrate to room temperature before use. Protect from light if the reagent will later be conjugated to a fluorophore. This product is intended for research use only and is not approved for diagnostic, therapeutic, or clinical applications.