Anti-Chk2 (phospho-T387) Antibody

This phospho-specific polyclonal reagent from Antibodies.com is raised in rabbit and selectively recognizes Chk2 when phosphorylated at threonine 387, a modification associated with activation of the kinase in the DNA damage response. Supplied as 100 µl of unconjugated antibody at 1 mg/ml in phosphate buffered saline (pH 7.2) with 0.05% sodium azide as preservative, it is validated for immunohistochemistry on formalin-fixed tissue sections and cross-reacts with human, mouse, and rat samples. The reagent supports studies of ATM-Chk2 signaling, G1/S and G2/M checkpoint control, and the cellular response to genotoxic stress, making it useful in oncology, DNA repair, and cell cycle research. Refrigerate on receipt; aliquot before use if repeated freeze-thaw cycles are expected, and protect from light to preserve long-term stability of the conjugate-free preparation.