Anti-CHD5 Antibody

From Antibodies.com, this polyclonal primary antibody targets CHD5 (Chromodomain Helicase DNA-binding protein 5), a member of the CHD chromatin remodeler family that has been characterized as a tumor suppressor mapped to human chromosome 1p36. The unconjugated reagent is supplied as 100 µl at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.3, packaged as a single-use vial.

Raised in rabbit, the antibody detects endogenous CHD5 in human, mouse, and rat samples and is validated for western blot analysis of cell lysates and tissue extracts. CHD5 biology intersects with chromatin remodeling, neuronal differentiation, and DNA damage response pathways, and the protein's frequent loss in neuroblastoma and several other malignancies has made it a focal target in cancer research laboratories studying 1p36 deletions, gene silencing events, and tumor suppressor networks.

Store refrigerated at 4 °C; aliquot upon receipt to limit repeated freeze-thaw cycles of the antibody solution. Intended for research use only.