Anti-CHD5 Antibody

Chromodomain helicase DNA-binding protein 5 (CHD5) is a chromatin remodeler widely studied for its role as a tumor suppressor in neural and hematopoietic tissues. This polyclonal reagent from Antibodies.com was raised in rabbit and is affinity-purified to recognize the human CHD5 protein in western blot workflows. The antibody is supplied as an unconjugated IgG preparation in a 50 µl vial, ready to dilute into standard immunoblotting buffers and detection chemistries.

CHD5 maps to chromosome 1p36, a region that is frequently deleted or silenced in neuroblastoma and several other cancers, and it influences downstream signaling linked to p53 activation, cell cycle progression, and apoptosis. Researchers working on chromatin remodeling, tumor suppressor biology, neuronal differentiation, and cancer genomics use this reagent to probe CHD5 expression across cell lines and primary tissue lysates. For best results, aliquot upon receipt and store at -20 °C, limiting repeated freeze-thaw cycles to preserve antibody titer across multiple experiments.