Anti-CHAF1B Antibody

Produced in rabbit as a polyclonal reagent against the human CHAF1B target, this unconjugated primary antibody from Antibodies.com supports chromatin biology and DNA replication research. Validated for Western blot and immunofluorescence workflows, it allows detection of endogenous CHAF1B in cultured human cells and tissue sections. CHAF1B is the p60 subunit of chromatin assembly factor-1 (CAF-1), a histone chaperone complex that deposits newly synthesized H3.1-H4 dimers onto replicating DNA and contributes to nucleotide excision repair pathways. Each vial contains 50 µl of liquid antibody stock, sufficient for multiple immunoblotting and IF experiments. For storage, aliquot upon arrival and freeze at -20 degrees C; limit freeze-thaw cycles to preserve reagent performance. Intended for research use only, the reagent is a practical tool for studies of replication-coupled chromatin assembly, histone deposition dynamics, and CHAF1B expression profiling in proliferating cell populations.