Anti-CGB Antibody

The CGB antibody from Antibodies.com targets the beta subunit of human chorionic gonadotropin (β-hCG), a 145-amino-acid glycoprotein encoded within the CGB gene cluster on chromosome 19q13.3. This Rabbit polyclonal reagent is supplied as an unconjugated IgG preparation in a 50 µl vial, suitable for Western blot and immunohistochemistry workflows on human tissue or cell-derived samples. β-hCG is clinically significant as a pregnancy marker and as a tumor-associated antigen expressed by trophoblastic and germ cell tumors, so the antibody is often used in placental pathology studies, germ cell tumor diagnostics, and investigations of trophoblastic differentiation. The polyclonal format allows recognition of multiple epitopes within the β-subunit, which can be advantageous when examining processed or truncated forms of the hormone. For detection, common chromogenic or fluorescent secondary reagents against Rabbit IgG are paired with the unconjugated primary, and antigen retrieval protocols appropriate for formalin-fixed tissue are recommended for IHC applications.