Anti-CETP Antibody

CETP (Cholesteryl Ester Transfer Protein) plays a central role in reverse cholesterol transport and the equilibration of neutral lipids between HDL and apoB-containing lipoproteins. Research into this protein underpins work on cardiovascular risk, atherosclerosis progression, and lipid metabolism, and it remains a translational target for inhibitor therapeutics. Antibodies.com offers this rabbit polyclonal anti-CETP reagent, supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, in a 100 µl vial. The unconjugated antibody was raised in rabbit and is validated for Western blot and immunohistochemistry on human samples, supporting studies of hepatic, adipose, and macrophage CETP expression in disease models and patient-derived tissues. Cited applications include characterization of CETP-mediated HDL particle remodeling, evaluation of candidate CETP-inhibitor compounds, and immunohistochemistry on formalin-fixed paraffin-embedded sections after antigen retrieval. For Western blotting, the reagent is typically titrated across a dilution series to optimize signal on cell lysates or tissue homogenates. Store at -20 °C in working aliquots to limit freeze-thaw cycles and protect from light; the glycerol-containing buffer preserves antibody activity during frozen storage.