Anti-CES2 Antibody

CES2 (Carboxylesterase 2) is a serine hydrolase enzyme primarily expressed in the liver and gastrointestinal tract, where it catalyzes the hydrolysis of ester and amide bonds in xenobiotics and therapeutic agents. This unconjugated rabbit polyclonal reagent from Antibodies.com targets the human CES2 protein and is validated for western blot, immunohistochemistry, and immunofluorescence workflows. Supplied as 100 µl of polyclonal antiserum raised in rabbit, the antibody enables investigators to map CES2 expression patterns relevant to drug metabolism, hepatic and intestinal physiology, and the intracellular activation of prodrugs such as irinotecan. The unconjugated format offers flexibility for downstream labeling, allowing researchers to pair the antibody with their preferred secondary reagents for chromogenic, fluorescent, or chemiluminescent readouts depending on the experimental design.