Anti-CEP120 Antibody

The CEP120 protein (also called CCDC100) is a centrosomal component essential for centriole biogenesis, daughter centriole formation, and primary cilium assembly. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against CEP120 and validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples.

Provided at 50 µL per vial, the antibody is supplied as a polyclonal antiserum fraction intended for research use only. It performs well on lysates from proliferating cell lines, where CEP120 appears as a roughly 120 kDa band in Western blot, and labels centrosomes in tissue sections by IHC. Users typically aliquot upon arrival to limit freeze-thaw cycles and store the vial at -20 °C, with brief 4 °C use; protect from light to preserve antibody integrity.

Published work has linked CEP120 function to early centriole assembly steps and to the recruitment of downstream factors such as CPAP/CENPJ and CEP295 to the nascent procentriole, making this Antibodies.com reagent useful for studies of cell division, ciliogenesis, and ciliopathy mechanisms, including Joubert syndrome and short-rib thoracic dysplasia models.