Anti-CEACAM6 Antibody

CEACAM6 (also called CD66c or NCA) is a GPI-anchored cell-surface glycoprotein of the CEA family that is widely profiled as a marker in epithelial cancers, including pancreatic, colorectal, breast, and non-small cell lung carcinoma, and that also contributes to innate immune cell signaling. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against human CEACAM6 and validated for western blot detection across Human, Mouse, and Rat samples, supporting cross-species studies of tumor biology, mucosal inflammation, and granulocyte function.

The antibody is supplied as 100 µl of stock at 1 mg/ml in phosphate buffered saline containing 15 mM sodium azide at approximately pH 7.2. Because the reagent is unconjugated, end users can pair it with HRP-, fluorophore-, or biotin-labelled secondary antibodies of their choice, adapting it to chemiluminescent western blot workflows or other downstream readouts. The polyclonal format recognizes multiple epitopes on the CEACAM6 ectodomain, which helps when probing for isoform variants, proteolytic fragments, or distinct subcellular pools in cell lysate preparations.

Common research uses include profiling CEACAM6 in pancreatic ductal adenocarcinoma cell lines, examining its role as a co-receptor during bacterial-host attachment, and tracking neutrophil CEACAM6 upregulation in inflammatory disease models. Reactivity across Human, Mouse, and Rat lets investigators move between patient-derived samples, mouse xenograft or knockout tissue, and rat injury models in translational programs. The vial should be kept refrigerated in the dark, with working aliquots prepared on first use to limit freeze-thaw cycles of the master stock. For research use only.