Anti-CDT2 Antibody

This rabbit polyclonal antibody from Antibodies.com recognizes CDT2, also known as DTL (denticleless protein homolog) and DCAF2, a substrate adaptor for the CRL4 E3 ubiquitin ligase complex. CDT2 directs the ubiquitin-mediated turnover of substrates such as Cdt1, p21 (CDKN1A), and Set8, linking chromatin licensing to S-phase entry, DNA replication, and the DNA damage response.

Supplied as 100 µl of liquid IgG in an unconjugated format, the reagent supports western blot, immunoprecipitation, immunofluorescence, and flow cytometry workflows. The antibody has been validated across human, mouse, rat, and hamster samples, making it a flexible option for comparative cell cycle and DNA repair studies.

For best results, store aliquots frozen at -20 °C and limit freeze-thaw cycles to preserve activity. The expected band size in western blot is approximately 79 kDa, consistent with the predicted molecular mass of full-length human CDT2.