Anti-CDKN2C Antibody

Rabbit polyclonal anti-CDKN2C antibody from Antibodies.com, supplied as 100 µL of unconjugated antisera for use in western blot and immunofluorescence workflows. CDKN2C (also called p18INK4c) is a member of the INK4 family of cyclin-dependent kinase inhibitors that binds CDK4 and CDK6 to enforce the G1/S cell cycle checkpoint, and it is studied as a tumor suppressor in contexts ranging from hepatocellular carcinoma and lymphoid malignancies to pituitary and pancreatic development.

This reagent was raised in rabbit and validated for detection of the human, mouse, and rat proteins, making it useful for comparative studies across model systems. Researchers commonly apply it to investigate p18INK4c expression and regulation in proliferating versus quiescent cells, loss of heterozygosity in tumor samples, and CDK inhibitor reactivation during senescence or differentiation. The unconjugated format supports flexible secondary antibody pairing, and the polyclonal profile increases the chance of recognizing multiple epitopes on the target for both immunoblotting of cell lysates and imaging of fixed tissue or cultured cells. For routine handling, store the vial refrigerated and protect from light, and aliquot if repeated freeze-thaw cycles are anticipated.