Anti-CDKN1B Antibody

The CDKN1B (p27Kip1) protein is a cyclin-dependent kinase inhibitor that regulates the G1/S cell cycle transition and acts as a tumor suppressor in many tissue types. This unconjugated rabbit polyclonal IgG antibody from Antibodies.com recognizes CDKN1B and is validated for Western blot detection in human, mouse, and rat samples. Supplied as 200 µl of liquid reagent, the polyclonal antibody supports studies of cell proliferation, apoptosis, and oncogenic signaling pathways.

Researchers use this reagent to monitor CDK inhibitor expression across tumor and normal tissue lysates, and to investigate how p27 levels shift in response to drug treatments or genetic manipulations involving cyclin-CDK complex activity. For consistent results, store aliquots refrigerated and avoid repeated freeze-thaw cycles to preserve antibody activity across multiple blotting experiments.