Anti-CDKN1A Antibody

The Antibodies.com polyclonal antibody recognizes CDKN1A, the p21CIP1/WAF1 cyclin-dependent kinase inhibitor that enforces the G1/S cell cycle checkpoint downstream of p53 signaling. Supplied as 100 ul of unconjugated rabbit antiserum, the reagent is validated for Western blot, immunohistochemistry, and immunofluorescence detection of endogenous CDKN1A in Human, Mouse, and Rat samples. Researchers apply this antibody to study DNA damage-induced cell cycle arrest, replicative and oncogene-induced senescence, and p53-p21 tumor suppressor pathway activity across cancer biology and ageing research models. As an unconjugated primary antibody, the reagent is also compatible with downstream detection chemistries, including HRP, alkaline phosphatase, and fluorophore-conjugated secondary antibodies, allowing flexible assay design for both chromogenic and fluorescence-based imaging workflows.