Anti-CDK6 Antibody

CDK6 (Cyclin-Dependent Kinase 6) is a serine/threonine kinase that partners with cyclin D to drive the G1 to S phase transition of the cell cycle by phosphorylating retinoblastoma (Rb) protein. This Rabbit polyclonal antibody from Antibodies.com recognizes CDK6 and is validated for western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples.

Produced in rabbit as an unconjugated polyclonal reagent, the antibody is supplied as a 100 µl vial and is intended for research use only in studies examining cell cycle progression, Rb/E2F signaling, and CDK6-dependent oncogenic programs. Typical applications include profiling CDK6 expression in tumor tissue sections, confirming protein levels in lysates from proliferating cells, and localizing CDK6 in fixed cells by immunofluorescence.

CDK6 is frequently overexpressed or amplified in lymphoid malignancies, glioblastoma, and certain breast cancers, making this Antibodies.com reagent useful for translational oncology projects investigating cell cycle deregulation and therapeutic response to small-molecule CDK4/6 inhibitors.