Anti-CDK5RAP3 Antibody

CDK5 regulatory subunit-associated protein 3 (CDK5RAP3), also referenced as C53 or LZAP in earlier literature, is a regulatory factor implicated in DNA damage response, cell cycle checkpoint control, and modulation of NF-kappa-B signaling. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against the human target and validated for Western blot and immunohistochemistry applications, supporting research into CDK5RAP3's tumor suppressor function across cancer cell models and patient tissue specimens. Supplied as 100 ul of polyclonal antiserum, the antibody recognizes CDK5RAP3 expressed in human samples and is frequently cited in studies of hepatocellular carcinoma, head and neck squamous cell carcinoma, and breast cancer, where reduced CDK5RAP3 levels have been linked to tumor progression and poorer clinical outcome. The unconjugated format allows flexible pairing with secondary antibodies for chromogenic or fluorescent detection across individual laboratory protocols.