Anti-CDK5 Antibody [Assigned #A10814]

Offered as a rabbit monoclonal IgG that recognises cyclin-dependent kinase 5 (CDK5), this unconjugated primary antibody from Antibodies.com is supplied in a 100 µL vial and validated for western blot, immunohistochemistry, and immunoprecipitation workflows on human, mouse, and rat samples. The reagent detects the approximately 33 kDa CDK5 band in detergent-solubilised whole-cell lysates and on paraformaldehyde-fixed brain tissue sections, supporting neuroscience and oncology programmes that track neuronal migration, axon guidance, synaptic plasticity, and apoptosis.

Because CDK5 is regulated by the neuronal activators p35 and p39, along with the p25 cleavage fragment implicated in aberrant tau phosphorylation, the antibody is widely adopted in Alzheimer's disease, Parkinson's disease, and glioblastoma research. The unconjugated format pairs cleanly with HRP, fluorophore, or biotin secondaries for flexible signal development on membranes and tissue. Aliquot on first use, refrigerate for short-term handling, store at -20°C for longer-term stability, and limit freeze-thaw cycles to preserve binding activity. For research use only.