Anti-Cdk5 Antibody

Raised in rabbit and affinity-purified by epitope-specific chromatography, this polyclonal reagent from Antibodies.com is directed against cyclin-dependent kinase 5 (Cdk5) and is offered at the 50 µl pack size. The unconjugated IgG is supplied as a liquid formulation at 1 mg/ml in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, and the immunogen is a synthetic peptide derived from human Cdk5 around the non-phosphorylation site of tyrosine15. According to the manufacturer, the antiserum specifically detects endogenous levels of the Cdk5 protein and has been validated for Western blotting, immunohistochemistry and ELISA workflows, with cross-reactivity demonstrated on human, mouse and rat samples, making it suitable for studies spanning cell-culture models through to rodent tissue. As a polyclonal preparation, the reagent recognizes multiple epitopes on the target, which can be advantageous when analysing post-translational modifications or splice variants of the kinase. Typical short-term storage is at 4 °C, with longer term aliquoting recommended at -20 °C to preserve activity, avoiding repeated freeze-thaw cycles. Each lot is dispatched from Antibodies.com's logistics hub in St. Louis, Missouri, with a stated lead time of 6–9 business days plus applicable freight and packing charges, and the product is backed by the supplier's published performance guarantee. The catalogue entry carries the A36003 reference for traceability across purchase orders, and the antibody is listed within the Primary Antibodies category alongside related CDK5 reagents, allowing researchers to source isotype-matched controls from the same range. For laboratories studying neuronal development, neurodegenerative disease models or cell-cycle signalling, this reagent provides a flexible, unconjugated format that can be paired with secondary detection chemistries of choice without interference from carrier fluorophores or enzymes.